| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Tony Gonsolin
IL-15
| SP | 79 | 4 | 4 | 4.44 | 1.27 | 68 | 27 |
| |
| 2 |
Dustin May
| SP | 80 | 5 | 4 | 3.60 | 1.18 | 80 | 27 |
| 3 |
Tyler Glasnow
IL-15
| SP | 136 | 10 | 6 | 3.24 | 1.08 | 168 | 40 |
| 4 |
Roki Sasaki
| SP | 129 | 9 | 7 | 3.63 | 1.16 | 150 | 40 |
| 5 |
Yoshinobu Yamamoto
| SP | 154 | 11 | 7 | 3.45 | 1.12 | 160 | 40 |
| 6 |
Bobby Miller
| SP | 46 | 3 | 2 | 4.11 | 1.26 | 44 | 16 |
| 7 |
Landon Knack
| SP | 48 | 2 | 2 | 4.31 | 1.25 | 47 | 15 |
| 8 |
Justin Wrobleski
| SP | 35 | 2 | 2 | 4.11 | 1.31 | 32 | 13 |
| 9 |
Blake Snell
IL-15
| SP | 158 | 12 | 7 | 3.42 | 1.20 | 206 | 70 |
| 10 |
Shohei Ohtani
| SP | 102 | 7 | 5 | 3.44 | 1.14 | 118 | 35 |
| 11 |
Clayton Kershaw
IL-60
| SP | 57 | 4 | 3 | 3.95 | 1.21 | 52 | 16 |