| | Player |
POS
| IP | W | L | ERA | WHIP | K | BB |
| 1 |
Eric Lauer
| SP | 41 | 2 | 2 | 5.01 | 1.38 | 38 | 16 |
| |
| 2 |
Kevin Gausman
| SP | 106 | 6 | 6 | 4.57 | 1.28 | 105 | 33 |
| |
| 3 |
Chris Bassitt
| SP | 99 | 6 | 6 | 4.54 | 1.31 | 88 | 35 |
| 4 |
Jose Berrios
| SP | 97 | 6 | 7 | 4.93 | 1.35 | 79 | 31 |
| 5 |
Bowden Francis
IL-15
| SP | 59 | 3 | 4 | 5.09 | 1.30 | 51 | 19 |
| 6 |
Easton Lucas
| SP | 13 | 1 | 1 | 4.51 | 1.35 | 13 | 6 |
| 7 |
Max Scherzer
IL-60
| SP | 75 | 5 | 5 | 4.47 | 1.19 | 78 | 23 |
| 8 |
Alek Manoah
IL-60
| SP | 15 | 1 | 1 | 4.67 | 1.34 | 14 | 7 |